Laboratório Nacional
de Luz Síncrotron

English

PUBLICAÇÕES

VOLTAR

PUBLICAÇÕES

Abaixo está disponível a lista de artigos científicos produzidos com dados obtidos nas instalações desta Linha de Luz e publicados em periódicos indexados pela base de dados Web of Science.

Atenção Usuários: Dada a importância dos resultados científicos anteriores para a processo geral de avaliação das propostas, recomenda-se que os Usuários verifiquem e atualizem suas publicações tanto no portal SAU Online quanto na base de dados da Biblioteca do CNPEM. As atualizações da base de dados da biblioteca devem ser feitas enviando a informação bibliográfica completa para a Biblioteca (biblioteca@cnpem.br). As publicações são incluídas após checagem pela equipe da biblioteca e pela coordenação das linhas de luz. 

 

LISTA DE PUBLICAÇÕES

 

2018

Toyama, D.; Morais, M. A. B.de ; Ramos, F. C.; Zanphorlin, L. M.; Tonoli, C. C. C.; Balula, A. F.; Miranda, F. P. de; Almeida, Vi. M.; Marana, S, R.; Ruller, R.; Murakami, M. T.; Henrique-Silva, F.. A novel beta-glucosidase isolated from the microbial metagenome of Lake Poraque (Amazon, Brazil), Biochimica et Biophysica Acta- Proteins and Proteomics, v. 1866, n. 4, p. 569-579, 2018. DOI: 0.1016/j.bbapap.2018.02.001

Barros, A.C.; Takeda, A. A. S.; Dreyer, T. R.; Velazquez- Campoy, A.; Kobe, B.; Fontes, M. R. de M.. DNA mismatch repair proteins MLH1 and PMS2 can be imported to the nucleus by a classical nuclear import pathway, Biochimie, v. 146, p. 87-96, 2018. DOI: 10.1016/j.biochi.2017.11.013

Ribeiro Filho, H. V.; Videira, N. B.; Bridi, A. V.; Tittanegro, T. H.; Batista, F. A. H.; Pereira, J. G. C.; Oliveira, P. S. L.; Bajgelman, M. C.; Le Maire, A.; Figueira. A. C. M.. Screening for PPAR Non-Agonist Ligands Followed by Characterization of a Hit, AM-879, with Additional No-Adipogenic and cdk5-Mediated Phosphorylation Inhibition Properties, Frontiers in Endocrinology, v. 9, p. 11, 2018. DOI: 10.3389/fendo.2018.00011

Salvador, G. H. M.; Santos, J. I.; Borges, R. J.; Fontes, M. R. de M.. Structural evidence for a fatty acid-independent myotoxic mechanism for a phospholipase A(2)-like toxin, Biochimica et Biophysica Acta- Proteins and Proteomics, v. 1866, n. 3, p. 473-481, 2018. DOI: 10.1016/j.bbapap.2017.12.008

Machado, A. T.P.; Silva, M. M. ; Iulek, J.. Structural studies of glyceraldehyde-3-phosphate dehydrogenase from Naegleria gruberi, the first one from phylum Percolozoa, Biochimica et Biophysica Acta- Proteins and Proteomics, v. 1866, n. 5-6, p. 581-588, 2018. DOI: 10.1016/j.bbapap.2018.02.006

2017

Machado, A. T.P.; Fonseca, E. M. B.; Reis, M. A.; Saraiva, A. M.; Santos, C. A.; Toledo, M. A. S.; Polikarpov, I.; Souza, A. P.; Aparicio, R.; Iulek, J.. Conformational variability of the stationary phase survival protein E from Xylella fastidiosa revealed by X-ray crystallography, small-angle X ray scattering studies, and normal mode analysis, Proteins-Structure Function and Bioinformatics, v. 85, n. 10, p. 1931-1943, 2017. DOI: 10.1002/prot.25347

Soprano, A. S.; Giuseppe, P. O.; Shimo, H. M.; Lima, T. B.; Batista, F. A. H.; Righetto, G. L.; Pereira, J. G. C.; Granato, D. C.; Nascimento, A. F. Z.; Gozzo, F. C.; Oliveira, P. S. L.; Figueira. A. C. M.; Smetana, J. H. C.; Paes Leme, A. F.; Murakami, M. T.; Benedetti, C. E.. Crystal Structure and Regulation of the Citrus Pol III Repressor MAF1 by Auxin and Phosphorylation, Structure, v. 25, n.9, p. 1360-1370, 2017. DOI: 10.1016/j.str.2017.07.004

Pinto-Jr., V. R.; Santiago, M. Q.; Nobre, C.B.; Osterne, V. J. S.; Leal, R. B.; Cajazeiras, J. B.; Lossio, C. F.; Rocha, B. A. M.; Martins, M. G. Q.; Nobre, C. A. S.; Silva, M. T. L.; Nascimento, K. S.; Cavada, B. S.. Crystal structure of Pisum arvense seed lectin (PAL) and characterization of its interaction with carbohydrates by molecular docking and dynamics, Archives of Biochemistry and Biophysics, v. 630, p. 27-37, 2017. DOI: 10.1016/j.abb.2017.07.013

Godoy, A. S.; Lima, G. M. A.; Oliveira, K. I. Z.; Torres, N. U.; Maluf, F. V.; Guido, R. V. C.; Oliva, G.. Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase, Nature Communications, v. 8, p. 14764, 2017. DOI: 10.1038/ncomms14764

Borges, R. J.; Cardoso, F. F.; Fernandes, C. A. H.; Dreyer, T. R.; Moraes, D. S. de; Floriano, R.; Rodrigues-Simioni, L.; Fontes, M. R. M.. Functional and structural studies of a Phospholipase A(2)-like protein complexed to zinc ions: Insights on its myotoxicity and inhibition mechanism, Biochimica et Biophysica Acta. General Subjects, v. 1861, n. 1, p. 3199-3209, 2017. DOI: 10.1016/j.bbagen.2016.08.003

Torquato, R. J. S.; Lu, S.; Martins, N. H.; Tanaka, A. S.; Pereira, P. J. B.. High-resolution structure of a Kazal-type serine protease inhibitor from the dengue vector Aedes aegypti, Acta Crystallographica Section F-Structural Biology Communications, v. 73, n. 8, p. 469-475, 2017. DOI: 10.1107/S2053230X17010007

Nascimento, K. S.; Santiago, M. Q.; Pinto-Jr., V. R.; Osterne, V. J. S.; Martins, F. W. V.; Nascimento, A. P. M.; Wolin, I. A. V.; Heinrich, I. A.; Martins, M. G. Q.; Silva, M. T. L.; Lossio, C. F.; Rocha, C. R. C.; Leal, R. B.; Cavada, B. S.. Structural analysis of Dioclea lasiocatpa lectin: A C6 cells apoptosis-inducing protein, International Journal of Biochemistry & Cell Biology, v. 92, p. 79- 89, 2017. DOI: 10.1016/j.biocel.2017.09.014

Contesini, F. J.; Liberato, M. V.; Rubio, M. V.; Calzado, F.; Zubieta, M. P.; Riaño-Pachón, D. M.; Squina, F. M.; Bracht, F.; Skaf, M. S.; Damásio, A. R. de L.. Structural and functional characterization of a highly secreted alpha-L-arabinofuranosidase (GH62) from Aspergillus nidulans grown on sugarcane bagasse, Biochimica et Biophysica Acta- Proteins and Proteomics, v. 1865, n.12 , p. 1758-1769, 2017. DOI: 10.1016/j.bbapap.2017.09.001

Couñago, R. M.; Allerston, C. K.; Savitsky, P.; Azevedo, H.; Godoi, P. H.; Wells, C. I.; Mascarello, A.; Gama, F. H. de S.; Massirer, K. B.; Zuercher, W. J.; Guimarães, C. R. W.; Gileadi, O.. Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations, Scientific Reports, v. 7, p. 7501, 2017. DOI: 10.1038/s41598-017-07755-y

Scapin, S. M. N.; Souza, F. H. M.; Zanphorlin, L. M.; Almeida, T. S.; Sade, Y. B.; Cardoso, A. M.; Pinheiro, G. L.; Murakami, M. T.. Structure and function of a novel GH8 endoglucanase from the bacterial cellulose synthase complex of Raoultella ornithinolytica, PloS One, v. 12, n. 4, p. e0176550, 2017. DOI: 10.1371/journal.pone.0176550

Campos, B.; Tramontina, R.; Cairo, J. P. L. F.; Liberato, M. V.; Mandelli, F.; Sousa, A.; Santos, S.; Rabelo, S. C.; Ienczak, J. L.; Ruller, R.; Damásio, A. R. de L.; Squina, F. M.. The Coptotermes gestroi aldo-keto reductase: a multipurpose enzyme for biorefinery applications, Biotechnology for Biofuels, v. 10, p. 4, 2017. DOI: 10.1186/s13068-016-0688-6

2016

Giuseppe, P. O.; Santos, M. L.; Sousa, S. M.; Koch, K. E.; Yunes, J. A.; Aparicio, R.; Murakami, M. T.. A comparative structural analysis reveals distinctive features of co-factor binding and substrate specificity in plant aldo-keto reductases, Biochemical and Biophysical Research Communications, v. 474, n. 4, p. 696-701, 2016. DOI: 10.1016/j.bbrc.2016.05.011

Campos, B. M.; Liberato, M. V.; Alvarez, T.M.; Zanphorlin, L. M.; Ematsu, G. C.; Barud, H. S.; Polikarpov, I.; Ruller, R.; Gilbert, H. J.; Zeri, A. C. de M.; Squina, F. M.. A Novel Carbohydrate-binding Module from Sugar Cane Soil Metagenome Featuring Unique Structural and Carbohydrate Affinity Properties, Journal of Biological Chemistry, v. 291, n. 45, p. 23734-237. DOI: 10.1074/jbc.m116.744383

Silva, D. C.; Fontes, G. N.; Erthal, L. C. S.; Lima, L. M. T. R.. Amyloidogenesis of the amylin analogue pramlintide, Biophysical Chemistry, v. 219, p. 1-8, 2016. DOI: 10.1016/j.bpc.2016.09.007

Santos, C. A.; Zanphorlin, L. M.; Crucello, A.; Tonoli, C. C. C.; Ruller, R.; Horta, M. A. C.; Murakami, M. T.; Souza, A. P.. Crystal structure and biochemical characterization of the recombinant ThBgl, a GH1 beta-glucosidase overexpressed in Trichoderma harzianum under biomass degradation conditions, Biotechnology for Biofuels, v. 9, p. 71, 2016. DOI: 10.1186/s13068-016-0487-0

Jardim, P.; Santos, I. C. S. da; Barbosa, J. A. R. G.; Freitas, S. M. de; Valadares, N. F.. Crystal structure of VapC21 from Mycobacterium tuberculosis at 1.31 angstrom resolution, Biochemical and Biophysical Research Communications, v. 478, n. 3, p. 1370-1375, 2016. DOI: 10.1016/j.bbrc.2016.08.130

Penteado, R. F.; Martini, V. P.; Iulek, J.. Crystallization and Crystallographic Analyses of Triosephosphate Isomerase from Naegleria gruberi, Revista Virtual de Química, v. 8, n. 6, p. 1835-1841, 2016. DOI: 10.21577/1984-6835.20160123

Boreiko, S.; Silva, M.. Crystallization and X Ray Diffraction Data Analyses of the Enzyme Urocanate Hydratase from Trypanosoma cruzi, Revista Virtual de Química, v. 8, n. 3, p. 678-686, 2016. DOI: 10.5935/1984-6835.20160051

Machado, A. T.P.; Silva, M.; Iulek, J.. Expression, purification, enzymatic characterization and crystallization of glyceraldehyde-3-phosphate dehydrogenase from Naegleria gruberi, the first one from phylum Percolozoa, Protein Expression and Purification, v. 125, p. 125-130, 2016. DOI: 10.1016/j.pep.2016.07.007

Bari, A.F.; Santiago, M. Q.; Osterne, V. J. S.; Pinto-Jr., V. R.; Silva Filho, J. C.; Debray, H.; Rocha, B. A. M.; Delatorre, P.; Teixeira, C. S.; Correia Neto, C.; Assreuy, A. M. S.; Nascimento, K. S.; Cavada, B. S.. Lectins from Parkia biglobosa and Parkia platycephala: A comparative study of structure and biological effects, International Journal of Biological Macromolecules, v. 92, p. 194-201, 2016. DOI: 10.1016/j.ijbiomac.2016.07.032

Matsuyama, B. Y.; Krasteva, P. V.; Baraquet, C.; Harwood, C. S.; Sondermann, H.; Navarro, M. V. A. S.. Mechanistic insights into c-di-GMP-dependent control of the biofilm regulator FleQ from Pseudomonas aeruginosa, Proceedings of The National Academy of Sciences of the United States of America, v.113, n. 2, p. E209-E218, 2016. DOI: 10.1073/pnas.1523148113

Almeida, A. C.; Osterne, V. J. S.; Santiago, M. Q.; Pinto-Jr., V. R.; Silva Filho, J. C.; Lossio, C. F.; Nascimento, F. L. F; Almeida, R. P. H.; Teixeira, C. S.; Leal, R. B.; Delatorre, P.; Rocha, B. A. M.; Assreuy, A. M. S.; Nascimento, K. S.; Cavada, B. S.. Structural analysis of Centrolobium tomentosum seed lectin with inflammatory activity, Archives of Biochemistry and Biophysics, v. 596, p. 73-83, 2016. DOI: 10.1016/j.abb.2016.03.001

Barros, A. C.; Takeda, A. A. S.; Dreyer, T. R.; Velazquez- Campoy, A.; Kobe, B.; Fontes, M. R. M.. Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence, Journal of Molecular Biology, v. 428, n. 10, p. 2120-2131, 2016. DOI: 10.1016/j.jmb.2016.01.019

Gallo, G.; Gilles, A.; Rangel, G.; Zelanis, A.; Mori, M. A.; Campos, C. B.; Wurtele, M.. Structural basis for dimer formation of the CRISPR-associated protein Csm2 of Thermotoga maritima, FEBS Journal, v. 283, n. 4, p. 694-703, 2016. DOI: 10.1111/febs.13621

Prado, R. A.; Santos, C. R.; Kato, D. I.; Murakami, M. T.; Viviani, V.R.. The dark and bright sides of an enzyme: a three dimensional structure of the N-terminal domain of Zophobas morio luciferase-like enzyme, inferences on the biological function and origin of oxygenase/luciferase activity, Photochemical & Photobiological Sciences, v. 15, n. 5, p. 654-665, 2016. DOI: 10.1039/c6pp00017g

Mariutti, R. B.; Ullah, A.; Araujo, G. C.; Murakami, M. T.; Arni, R. K.. Tyrosine binding and promiscuity in the arginine repressor from the pathogenic bacterium Corynebacterium pseudotuberculosis, Biochemical and Biophysical Research Communications, v. 475, n. 4, p. 350-355, 2016. DOI: 10.1016/j.bbrc.2016.05.091

2015

Campos, B. M.; Liberato, M. V.; Polikarpov, I.; Zeri, A. C. de M.; Squina, F. M.. Cloning, purification, crystallization and preliminary X-ray studies of a carbohydrate-binding module from family 64 (StX), Acta Crystallographica Section F-Structural Biology Communications, v. 71, pt. 3, p. 311-314, 2015. DOI: 10.1107/s2053230x15002198

Bernardes, A.; Textor, L. C.; Santos, Ja. C.; Cuadrado, N. H.; Kostetsky, E. Y.; Roig, M. G.; Bavro, V. N.; Muniz, J. R. C.; Shnyrov, V. L.; Polikarpov, I.. Crystal structure analysis of peroxidase from the palm tree Chamaerops excelsa, Biochimie, v. 111, p. 58-69, 2015. DOI: 10.1016/j.biochi.2015.01.014

Vieira, P. S.; Giuseppe, P. O.; Murakami, M. T.; Oliveira, A. H. C.. Crystal structure and biophysical characterization of the nucleoside diphosphate kinase from Leishmania braziliensis, BMC Structural Biology, v. 15, p. 1-12, 2015. DOI: 10.1186/s12900-015-0030-8

Ullah, A.; Mariutti, R. B.; Masood, R.; Caruso, I. P.; Costa, G. H. G.; Freitas, C. M. de; Santos, C. R.; Zanphorlin, L. M.; Mutton, M. J. R.; Murakami, M. T.; Arni, R. K.. Crystal structure of mature 2S albumin from Moringa oleifera seeds, Biochemical and Biophysical Research Communications, v. 468, n. 1-2, p. 365-371, 2015. DOI: 10.1016/j.bbrc.2015.10.087

Fonseca, E. M. B.; Trivella, D. B. B.; Scorsato, V.; Dias, M. P.; Bazzo, N. L.; Mandapati, K. R.; Oliveira, F. L.; Ferreira-Halder, C. V.; Pilli, R. A.; Miranda, P. C. M. L.; Aparicio, R.. Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates, Bioorganic & Medicinal Chemistry, v. 23, n. 15, p. 4462-4471, 2015. DOI: 10.1016/j.bmc.2015.06.017

Santos, Ja. C.; Bernardes, A.; Giampietro, L.; Ammazzalorso, A.; De Filippis, B.; Amore, R.; Polikarpov, I.. Different binding and recognition modes of GL479, a dual agonist of Peroxisome Proliferator-Activated Receptor alpha/gamma, Journal of Structural Biology, v. 191, n. 3, p. 332-340, 2015. DOI: 10.1016/j.jsb.2015.07.006

Furtado, G. P.; Santos, C. R.; Cordeiro, R. L.; Ribeiro, L. F.; Moraes, L. A. B.; Damásio, A. R. de L.; Polizeli, M. de L. T. M.; Lourenzoni, M. R.; Murakami, M. T.; Ward, R. J.. Enhanced xyloglucan-specific endo-beta-1,4-glucanase efficiency in an engineered CBM44-XegA chimera, Applied Microbiology and Biotechnology, v. 99, n. 12, p. 5095-5107, 2015. DOI: 10.1007/s00253-014-6324-0

Diogo, J. A.; Zanphorlin, L. M.; Sato, H. H.; Murakami, M. T.; Ruller, R.. Molecular cloning, overexpression, purification and crystallographic analysis of a GH43-xylosidase from Bacillus licheniformis, Acta Crystallographica Section F-Structural Biology Communications, v. F71, n. 8, p. 962-965, 2015. DOI: 10.1107/s2053230x15009978

Reis, R. A. G.; Lorenzato Jr., E.; Silva, V. C.; Nonato, M. C.. Recombinant production, crystallization and crystal structure determination of dihydroorotate dehydrogenase from Leishmania (Viannia) braziliensis, Acta Crystallographica Section F-Structural Biology Communications, v. 71, pt. 5, p. 547-552, 2015. DOI: 10.1107/s2053230x15000886

Fernandes, C. A. H.; Cardoso, F. F.; Cavalcante, W. L. G.; Soares, A. M.; Dal Pai, M.; Gallacci, M.; Fontes, M. R. M.. Structural basis for the inhibition of a phospholipase A(2)-like toxin by caffeic and aristolochic acids, PloS One, v. 10, n. 7, p. e0133370, 2015. DOI: 10.1371/journal.pone.0133370

Santos, C. R.; Cordeiro, R. de C. L.; Wong, D. W. S.; Murakami, M. T.. Structural Basis for Xyloglucan Specificity and alpha-D-Xylp(1 -> 6)-D-Glcp Recognition at the-1 Subsite within the GH5 Family, Biochemistry, v. 54, n. 10, p. 1930-1942, 2015. DOI: 10.1021/acs.biochem.5b00011

Vieira, P. S.; Giuseppe, P. O.; Oliveira, A. H. C.; Murakami, M. T.. The role of the C-terminus and Kpn loop in the quaternary structure stability of nucleoside diphosphate kinase from Leishmania parasites, Journal of Structural Biology, v. 192, n. 3, p. 336-341, 2015. DOI: 10.1016/j.jsb.2015.09.009

2014

Pádua, R. A. P. de; Nonato, M. C.. Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of recombinant human fumarase, Acta Crystallographica Section F-Structural Biology and Communications, v. 70, pt. 1, p. 120-122, 2014. DOI: 10.1107/s2053230x13033955

Campos, B. M.; Alvarez, T.M.; Liberato, M. V.; Polikarpov, I.; Gilbert, H. J.; Zeri, A. C. de M.; Squina, F. M.. Cloning, purification, crystallization and preliminary X-ray studies of a carbohydrate-binding module (CBM_E1) derived from sugarcane soil metagenome, Acta Crystallographica Section F-Structural Biology Communications, v. 70, pt. 9, p. 1232-1235, 2014. DOI: 10.1107/s2053230x14015520

Ullah, A.; Magalhães, G. S.; Masood, R.; Mariutti, R. B.; Coronado, M. A.; Murakami, M. T.; Barbaro, K. C.; Arni, R. K.. Crystallization and preliminary X-ray diffraction analysis of a novel sphingomyelinase D from Loxosceles gaucho venom, Acta Crystallographica Section F-Structural Biology Communications, v. F70, n. 10, p. 1418-1420, 2014. DOI: 10.1107/S2053230X14019207

Ullah, A.; Masood, R.; Spencer, P. J.; Murakami, M. T.; Arni, R. K.. Crystallization and preliminary X-ray diffraction studies of an L-amino-acid oxidase from Lachesis muta venom, Acta Crystallographica Section F-Structural Biology Communications, v. 70, pt. 11, p.1556-1559, 2014. DOI: 10.1107/S2053230X14017877

Segato, F.; Berto, G. L.; Araújo, E. A.; Muniz, J. R. C.; Polikarpov, I.. Expression, purification, crystallization and preliminary X-ray diffraction analysis of Aspergillus terreus endo-Beta-1,4-glucanase from glycoside hydrolase family 12, Acta Crystallographica Section F-Structural Biology Communications, v. 70, pt. 2, p. 267-270, 2014. DOI: 10.1107/s2053230x13034936

Santos, C. R.; Polo, C. C.; Costa, M. C. M. F.; Nascimento, A. F. Z.; Meza, A. N.; Cota, J.; Hoffmam, Z. B.; Honorato, R. V.; Oliveira, P. S. L.; Goldman, G. H.; Gilbert, H. J.; Prade, R. A.; Ruller, R.; Squina, F. M.; Wong, D. W. S.; Murakami, M. T.. Mechanistic strategies for catalysis adopted by evolutionary distinct family 43 arabinanases, Journal of Biological Chemistry, v. 289, n. 11, p. 7362-7373, 2014. DOI: 10.1074/jbc.m113.537167

Santos, C. R.; Hoffmam, Z. B.; Zanphorlin, L. M.; Assis, L.H.P.; Honorato, R. V.; Oliveira, P. S. L.; Ruller, R.; Murakami, M. T.. Molecular mechanisms associated with xylan degradation by xanthomonas plant pathogens, Journal of Biological Chemistry, v. 289, n. 46, p. 32186-32200, 2014. DOI: 10.1074/jbc.m114.605105

Costa, M. A. F.; Rodrigues, F. T. G.; Chagas, B. C. A.; Rezende, C. M. F.; Góes, A. M. de; Nagem, R. A. P.. Preliminary crystallographic studies of a Schistosoma mansoni antigen (Sm21.7) dynein light-chain (DLC) domain, Acta Crystallographica Section F-Structural Biology Communications, v. 70, pt. 6, p. 803-807, 2014. DOI: 10.1107/s2053230x14009273

Giuseppe, P. O.; Souza, T.A.C.B.; Souza, F. H. M.; Zanphorlin, L. M.; Machado, C. B.; Ward, R. J.; Jorge, J. A.; Furriel, R. P. M.; Murakami, M. T.. Structural basis for glucose tolerance in GH1 ß-glucosidases., Acta Crystallographica Section D-Biological Crystallography, v.70, p. 1631-1639, 2014. DOI: 10.1107/s1399004714006920

Bezerra, G. A.; Viertimayr, R.; Moura, T. R.; Delatorre, P.; Rocha, B. A. M.; do Nascimento, G. S.; Figueiredo, J. G.; Bezerra, I. G.; Teixeira, C. S.; Simões, R. C.; Nagano, C. S.; Alencar, N. M. N.; Gruber, K.; Cavada, B. S.. Structural studies of an anti-inflammatory lectin from Canavalia boliviana seeds in complex with dimannosides, PloS One, v. 9, n. 5, p. e97015, 2014. DOI: 10.1371/journal.pone.0097015

2013

Barbosa, J. A. R. G.; Whittaker, S. B. M.; Murakami, M. T.; Zeri, A. C. de M.; Benedetti, C. E.. A redox 2-Cys mechanism regulates the catalytic activity of divergent cyclophilins, Plant Physiology, v. 162, n. 3, p. 1311- 1323, 2013. DOI: 10.1104/pp.113.218339

Palmieri, L. de C.; Fávero-Retto, M. P.; Lourenço, D.; Lima, L. M. T. R.. A T3R3 hexamer of the human insulin variant B28Asp, Biophysical Chemistry, v. 173-174 , p. 1-7, 2013. DOI: 10.1016/j.bpc.2013.01.003

Romanello, L.; Bachega, J.F.R.; Cassago, A.; Brandão-Neto, J.; DeMarco, R.; Garratt, R. C.; Pereira, H. D´M.. Adenosine kinase from Schistosoma mansoni: structural basis for the differential incorporation of nucleoside analogues, Acta Crystallographica Section D-Biological Crystallography, v. 69, pt. 1, p. 126-136, 2013. DOI: 10.1107/s0907444912044800

de Morais, M. A. B.; Souza, T.A.C.B.; Murakami, M. T.. Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of the mitochondrial tryparedoxin peroxidase from Leishmania braziliensis, Acta Crystallographica Section F-Structural Biology and Communications, v. 69, pt. 4, p. 408-411, 2013. DOI: 10.1107/s1744309113003989

Ullah, A.; Souza, T.A.C.B.; Zanphorlin, L. M.; Mariutti, R. B.; Santana, V. S.; Murakami, M. T.; Arni, R. K.. Crystal structure of Jararacussin-I: the highly negatively charged catalytic interface contributes to macromolecular selectivity in snake venom thrombin-like enzymes, Protein Science, v. 22, p. 128-132, 2013. DOI: 10.1002/pro.2189

Araújo, E. A.; Tomazini Jr., A.; Kadowaki, M. A. S.; Murakami, M. T.; Polikarpov, I.. Crystallization and preliminary X-ray diffraction analysis of a new xyloglucanase from Xanthomonas campestris pv. campestris, Acta Crystallographica Section F-Structural Biology and Communications, v. 69, p. 676-678, 2013. DOI: 10.1107/S174430911301275X

Alvarez, T.M.; Goldbeck, R.; dos Santos, C. R.; Paixão, D. A. A.; Gonçalves, T. A.; Cairo, J. P. L. F.; Almeida, R. F.; Rocha, G. J. M.; Cota, J.; Büchli, F.; Citadini, A. P.; Ruller, R.; Polo, C. C.; Oliveira Neto, M.; Murakami, M. T.; Squina, F. M.. Development and biotechnological application of a novel endoxylanase family GH10 identified from sugarcane soil metagenome, PloS One, v. 8, n. 7, p. e70014, 2013. DOI: 10.1371/journal.pone.0070014

dos Reis, C. V.; Bernardes, A.; Polikarpov, I.. Expression, purification, crystallization and preliminary X-ray diffraction analysis of Bifidobacterium adolescentis xylose isomerase, Acta Crystallographica Section F-Structural Biology and Communications, v. 69, p. 588-591, 2013. DOI: 10.1107/s174430911301110x

Barsottini, M.R.O.; Oliveira, J. F.; Adamoski, D.; Teixeira, P.J.P.L.; Prado, P. F. V.; Tiezzi, H. O.; Sforça, M. L.; Cassago, A.; Portugal, R. V.; Oliveira, P. S. L.; Zeri, A. C. de M.; Dias, S. M. G.; Pereira, G. A. G.; Ambrosio, A. L. B.. Functional diversification of cerato-platanins in Moniliophthora perniciosa as seen by differential expression and protein function specialization, Molecular Plant-Microbe Interactions, v. 26, n. 11, p. 1281-1293, 2013. DOI: 10.1094/mpmi-05-13-0148-r

Textor, L. C.; Colussi, F.; Silveira, R. L.; Serpa, V. I.; Mello, B. L. S. de; Muniz, J. R. C.; Squina, F. M.; Pereira Jr., N.; Skaf, M. S.; Polikarpov, I.. Joint X-ray crystallographic and molecular dynamics study of cellobiohydrolase I from Trichoderma harzianum: deciphering the structural features of cellobiohydrolase catalytic activity, FEBS Journal, v. 280, n. 1, p. 56- 59, 2013. DOI: 10.1111/febs.12049

Bernardes, A.; Souza, P. C. T.; Muniz, J. R. C.; Ricci, C. G.; Ayers, S. D.; Parekh, N. M.; Godoy, A. S.; Trivella, D. B. B.; Reinach, P. S.; Webb, P.; Skaf, M. S.; Polikarpov, I.. Molecular mechanism of peroxisome proliferator-activated receptor alpha activation by WY14643: a new mode of ligand recognition and receptor stabilization, Journal of Molecular Biology, v. 425, n. 16 , p. 2878-2893, 2013. DOI: 10.1016/j.jmb.2013.05.010

Araújo, F. T.; Bolanos- Garcia, V. M.; Pereira, C. T.; Sanches, M.; Oshiro, E. E.; Ferreira, R. C. C.; Chigardze, D. Y.; Barbosa, J. A. R. G.; Ferreira, L. C. de S.; Benedetti, C. E.; Blundell, T. L.; Balan, A.. Structural and physiological analyses of the Alkanesulphonate-binding protein (SsuA) of the citrus pathogen Xanthomonas citri, PloS One, v. 8, n. 11, p. e80083, 2013. DOI: 10.1371/journal.pone.0080083

Nascimento, A. F. Z.; Trindade, D. M.; Tonoli, C. C. C.; Giuseppe, P. O.; Assis, L.H.P.; Honorato, R. V.; Oliveira, P. S. L.; Mahajan, P.; Burgess-Brown, N. A.; von Delft, F.; Larson, R. E.; Murakami, M. T.. Structural Insights into Functional Overlapping and Differentiation among Myosin V Motors, Journal of Biological Chemistry, v. 288, n. 47, p. 34131-34145, 2013. DOI: 10.1074/jbc.m113.507202

Murakami, M. T.; Rodrigues, N. C.; Gava, L. M.; Honorato, R. V.; Canduri, F.; Barbosa, L. R. S.; Oliva, G.; Borges, J. C.. Structural studies of the Trypanosoma cruzi Old Yellow Enzyme: insights into enzyme dynamics and specificity, Biophysical Chemistry, v. 184, p. 44- 53, 2013. DOI: 10.1016/j.bpc.2013.08.004

Alvarez, T.M.; Paiva, J. H.; Ruiz, D. M.; Cairo, J. P. L. F.; Pereira, I. O.; Paixão, D. A. A.; Almeida, R. F.; Tonoli, C. C. C.; Ruller, R.; Santos, C. R.; Squina, F. M.; Murakami, M. T.. Structure and function of a novel cellulase 5 from sugarcane soil metagenome, PloS One, v. 8, n. 12, p. e83635, 2013. DOI: 10.1371/journal.pone.0083635

Neves, D.; Job, V.; Dortet, L.; Cossart, P.; Dessen, A.. Structure of internalin InIK from the human pathogen Listeria monocytogenes, Journal of Molecular Biology, v. 425, n. 22, p. 4520-4529, 2013. DOI: 10.1016/j.jmb.2013.08.010

Valadares, N. F.; Oliveira-Silva, R.; Cavini, I. A.; Marques, I. A.; Pereira, H. D´M.; Soares-Costa, A.; Henrique-Silva, F.; Kalbitzer, H. R.; Munte, C. E.; Garratt, R. C.. X-ray crystallography and NMR studies of domain-swapped canecystatin-1, FEBS Journal, v. 280, n. 4, p. 1028-1038, 2013. DOI: 10.1111/febs.12095

Prates, E. T.; Stankovic , I.; Silveira, R. L.; Liberato, M. V.; Henrique-Silva, F.; Pereira Jr., N.; Polikarpov, I.; Skaf, M. S.. X-ray structure and molecular dynamics simulations of endoglucanase 3 from Trichoderma harzianum: structural organization and substrate recognition by endoglucanases that lack cellulose binding module, PloS One, v. 8, n. 3, p. e59069, 2013. DOI: 10.1371/journal.pone.0059069

2012

Reis, M. A.; Saraiva, A. M.; dos Santos, M. L.; de Souza, A. P.; Aparicio, R.. Crystallization and preliminary X-ray analysis of stationary phase survival protein E (SurE) from Xylella fastidiosa in two crystal forms, Acta Crystallographica Section F-Structural Biology Communications, v. 68, pt.4 , p. 464-467, 2012. DOI: 10.1107/s1744309112007129

Ullah, A.; Coronado, E.; Murakami, M. T.; Betzel, C.; Arni, R. K.. Crystallization and preliminary X-ray diffraction analysis of an L-amino-acid oxidase from Bothrops jararacussu venom, Acta Crystallographica Section F-Structural Biology Communications, v. 68, n. 2, p. 211-213, 2012. DOI: 10.1107/S1744309111054923

Liberato, M. V.; Generoso, W. C.; Malagó Jr., W.; Henrique-Silva, F.; Polikarpov, I.. Crystallization and preliminary X-ray diffraction analysis of endoglucanase III from Trichoderma harzianum, Acta Crystallographica Section F-Structural Biology and Communications, v. 68, pt. 3, p. 306-309, 2012. DOI: 10.1107/s1744309112000838

Ullah, A.; Souza, T.A.C.B.; Betzel, C.; Murakami, M. T.; Arni, R. K.. Crystallographic portrayal of different conformational states of a Lys49 phospholipase A(2) homologue: Insights into structural determinants for myotoxicity and dimeric configuration, International Journal of Biological Macromolecules, v. 51, n.3 , p. 209-214, 2012. DOI: 10.1016/j.ijbiomac.2012.05.006

Santos, C. R.; Paiva, J. H.; Sforça, M. L.; Neves, J. L.; Navarro, R. Z.; Cota, J.; Akao, P. K.; Hoffmam, Z. B.; Meza, A. N.; Smetana, J. H. C.; Nogueira, M. L. C.; Polikarpov, I.; Xavier Neto, J.; Squina, F. M.; Ward, R. J.; Ruller, R.; Zeri, A. C. de M.; Murakami, M. T.. Dissecting structure-function-stability relationships of a thermostable GH5-CBM3 cellulase from Bacillus subtilis 168, Biochemical Journal, v. 441, n. 1, p. 95-104, 2012. DOI: 10.1042/bj20110869

Trivella, D. B. B.; dos Reis, C. V.; Lima, L. M. T. R.; Foguel, D.; Polikarpov, I.. Flavonoid interactions with human transthyretin: combined structural and thermodynamic analysis, Journal of Structural Biology, v. 180, n. 1, p. 143-153, 2012. DOI: 10.1016/j.jsb.2012.07.008

Tada, S. F. S.; Saraiva, A. M.; Lorite, G. S.; Rosselli-Murai, L.K.; Pelloso, A. C.; Santos, M. L.; Trivella, D. B. B.; Cotta, M. A.; Souza, A. P.; Aparicio, R.. Initial crystallographic studies of a small heat-shock protein from Xylella fastidiosa, Acta Crystallographica Section F-Structural Biology Communications, v. 68, pt. , p. 535-539, 2012. DOI: 10.1107/S1744309112009347

Giuseppe, P. O.; Martins, N. H.; Meza, A. N.; dos Santos, C. R.; Pereira, H. M.; Murakami, M. T.. Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases, PloS One, v. 7, n. 9, e44282, 2012. DOI: 10.1371/journal.pone.0044282

Liberato, M. V.; Lin, J. Z.; Nascimento, A. S.; Ayers, S. D.; Cvoro, A.; Silveira, R. L.; Martinez, L.; Souza, P. C. T.; Saimdemberg, D. M.; Deng, T.; Amato, A. A.; Phillips, K. J.; Togashi, M.; Hsueh, W. A.; Palma, M.S.; Neves, F. A. R.; Skaf, M. S.; Webb, P.; Polikarpov, I.. Medium chain fatty acids are selective peroxisome proliferator activated receptor (PPAR) gamma activators and pan-PPAR partial agonists, PloS One, v. 7, n. 5, p. e36297, 2012. DOI: 10.1371/journal.pone.0036297

Cvoro, A.; Webb, P.; Puhl, A. C.; Bernardes, A.; Silveira, R. L.; Yuan, J.; Campos, J. L. O.; Saidemberg, D. M.; Palma, M.S.; Ayers, S. D.; Reinach, F. de C.; Skaf, M. S.; Polikarpov, I.. Mode of peroxisome proliferator-activated receptor gamma activation by luteolin, Molecular Pharmacology, v. 81, n. 6, p. 788-799, 2012. DOI: 10.1124/mol.111.076216

dos Santos, C. R.; Paiva, J. H.; Meza, A. N.; Cota, J.; Alvarez, T.M.; Ruller, R.; Prade, R. A.; Squina, F. M.; Murakami, M. T.. Molecular insights into substrate specificity and thermal stability of a bacterial GH5-CBM27 endo-1,4-Beta-D-mannanase, Journal of Structural Biology, v. 177, n. 2, p. 469-476, 2012. DOI: 10.1016/j.jsb.2011.11.021

Ullah, A.; Souza, T.A.C.B.; Masood, R.; Murakami, M. T.; Arni, R. K.. Purification, crystallization and preliminary X-ray diffraction analysis of a class P-III metalloproteinase (BmMP-III) from the venom of Bothrops moojeni, Acta Crystallographica Section F-Structural Biology and Communications, v. 68, pt.10 , p. 1222-1225, 2012. DOI: 10.1107/s1744309112036603

Barros, A.C.; Takeda, A. A. S.; Chang,C-W; Kobe, B.; Fontes, M. R. M.. Structural basis of nuclear import of flap endonuclease 1 (FEN1), Acta Crystallographica Section D-Biological Crystallography, v. 68, pt. 7, p. 743- 750, 2012. DOI: 10.1107/S0907444912010281

Ullah, A.; Souza, T.A.C.B.; Abrego, J. R. B.; Betzel, C.; Murakami, M. T.; Arni, R. K.. Structural insights into selectivity and cofactor binding in snake venom L-amino acid oxidases, Biochemical and Biophysical Research Communications, v. 421, n. 1, p. 124-128, 2012. DOI: 10.1016/j.bbrc.2012.03.129

Beton, D.; Guzzo, C. R.; Ribeiro, A. F.; Farah, C. S.; Terra, W. R.. The 3D structure and function of digestive cathepsin L-like proteinases of Tenebrio molitor larval midgut, Insect Biochemistry and Molecular Biology, v. 42, n. 9, p. 655-664, 2012. DOI: 10.1016/j.ibmb.2012.04.010

Santos, A. R. dos; Polo, C. C.; Corrêa, J. M.; Seixas, F. A. V.; Murakami, M. T.; Simão, R. C. G.. The accessory domain changes the accessibility and molecular topography of the catalytic interface in monomeric GH39 ss-xylosidases, Acta Crystallographica Section D-Biological Crystallography, v. 68, pt. 10, p. 1339-1345, 2012. DOI: 10.1107/s0907444912028491

Gomes, M. T. R.; Teixeira, R. D.; Lopes, M. T. P.; Nagem, R. A. P.; Salas, C. E.. X-ray crystal structure of CMS1MS2: a high proteolytic activity cysteine proteinase from Carica candamarcensis, Amino Acids, v. 43, n. 6, p. 2381-2391, 2012. DOI: 10.1007/s00726-012-1318-7

2011

Souza, D. P.; Andrade, M. O.; Alvarez-Martinez, C. E.; Arantes, G. M.; Farah, C. S.; Salinas, R. K.. A component of the Xanthomonadaceae type IV secretion system combines a VirB7 motif with a N0 domain found in outer membrane transport proteins, PLoS Pathogens, v. 7, n. 5, p. e1002031-1-18, 2011. DOI: 10.1371/journal.ppat.1002031

Alves, R. M.; Feliciano, P. R.; Sampaio, S. V.; Nonato, M. C.. A rational protocol for the successful crystallization of L-amino-acid oxidase from Bothrops atrox, Acta Crystallographica Section F-Structural Biology Communications, v. 67, Pt. 4, p. 472-478, 2011. DOI: 10.1107/s1744309111003770

Furtado, G. P.; Ribeiro, L. F.; Santos, C. R.; Tonoli, C. C. C.; Souza, A. R.; Oliveira, R. R.; Murakami, M. T.; Ward, R. J.. Biochemical and structural characterization of a Beta-1,3-1,4-glucanase from Bacillus subtilis 168, Process Biochemistry, v.46, n.5, p.1202-1206, 2011. DOI: 10.1016/j.procbio.2011.01.037

Sánchez-Quitian, Z.; Timmers, L. F. S. M.; Caceres, R. A.; Rehm, J. G.; Thompson, C. E.; Basso, L. A.; de Azevedo Jr., W. F.; Santos, D. S. dos. Crystal structure determination and dynamic studies of Mycobacterium tuberculosis Cytidine deaminase in complex with products, Archives of Biochemistry and Biophysics, v. 509, n. 1, p. 108-115, 2011. DOI: 10.1016/j.abb.2011.01.022

Rangel, T.B.A.; Assreuy, A. M. S.; Pires, A. F.; Carvalho, A.U.; Benevides, R. G.; Simões, R. C.; Silva, H. C.; Bezerra, M. J. B.; Nascimento, A. S. F.; Nascimento, K. S.; Nagano, C. S.; Sampaio, A. H.; Delatorre, P.; Rocha, B. A. M.; Fernandes, P. M. B.; Cavada, B. S.. Crystallization and characterization of an inflammatory lectin purified from the seeds of Dioclea wilsonii, Molecules, v. 16, n. 6, p.5087-5103, 2011. DOI: 10.3390/molecules16065087

Ullah, A.; Giuseppe, P. O.; Murakami, M. T.; Silva, D. T.; Wille, A. C. M.; Chaves-Moreira, D.; Gremski, L. H.; da Silveira, R. B.; Sennf-Ribeiro, A.; Chaim, O. M.; Veiga, S. S.; Arni, R. K.. Crystallization and preliminary X-ray diffraction analysis of a class II phospholipase D from Loxosceles intermedia venom., Acta Crystallographica Section F-Structural Biology Communications, v. 67, 234-236, 2011. DOI: 10.1016/s0167-4838(99)00120-x

Shimabuku, P. S.; Fernandes, C. A. H.; Magro, A. J.; Costa, T. R.; Soares, A. M.; Fontes, M. R. M.. Crystallization and preliminary X-ray diffraction analysis of a Lys49-phospholipase A(2) complexed with caffeic acid, a molecule with inhibitory properties against snake venoms, Acta Crystallographica Section F-Structural Biology Communications, v. 67, n. Pt 2, p. 249-252, 2011. DOI: 10.1107/s1744309110051407

Rustiguel, J. K. R.; Pinheiro, M. P.; Araújo, A. P. U.; Nonato, M. C.. Crystallization and preliminary X-ray diffraction analysis of recombinant chlorocatechol 1,2-dioxygenase from Pseudomonas putida, Acta Crystallographica Section F-Structural Biology Communications, v. 67, Pt. 4, p. 507-509, 2011. DOI: 10.1107/s174430911100635x

Postigo, M.P.; Krogh, R.; Terni, M.F.; Pereira, H. M.; Oliva, G.; Castilho, M. S.; Andricopulo, A. D.. Enzyme Kinetics, Structural Analysis and Molecular Modeling Studies on a Series of Schistosoma mansoni PNP Inhibitors, Journal of the Brazilian Chemical Society, v.22, n.3, P.583-591, 2011. DOI: 10.1590/s0103-50532011000300024

dos Santos, C. R.; Squina, F. M.; Meza, A. N.; Oldiges, D. P.; Paes Leme, A. F.; Ruller, R.; Mort, A. J.; Prade, R. A.; Murakami, M. T.. Functional and biophysical characterization of a hyperthermostable GH51 alpha-L-arabinofuranosidase from Thermotoga petrophila, Biotechnology Letters, v.33, n.1, p. 131-137, 2011. DOI: 10.1007/s10529-010-0409-3

Souza, T.A.C.B.; Trindade, D. M.; Tonoli, C. C. C.; Santos, C. R.; Ward, R. J.; Arni, R. K.; Oliveira, A. H. C.; Murakami, M. T.. Molecular adaptability of nucleoside diphosphate kinase b from Trypanosomatid parasites: stability, oligomerization and structural determinants of nucleotide binding, Molecular BioSystems, v.7, n.7, p. 2189-2195, 2011. DOI: 10.1039/c0mb00307g

Bleicher, L.; Prates, E. T.; Gomes, C. F.; Silveira, R. L.; Nascimento, A. S.; Rojas, A. L.; Golubev, A. M.; Martinez, L.; Skaf, M. S.; Polikarpov, I.. Molecular basis of the thermostability and thermophilicity of laminarinases: X-ray structure of the hyperthermostable laminarinase from rhodothermus marinus and molecular dynamics simulations, Journal of Physical Chemistry B, v. 115, n. 24, p. 7940- 7949, 2011. DOI: 10.1021/jp200330z

Martins, N. H.; Meza, A. N.; Santos, C. R.; Giuseppe, P. O.; Murakami, M. T.. Molecular cloning, overexpression, purification, crystallization and preliminary X-ray diffraction analysis of a purine nucleoside phosphorylase from Bacillus subtilis strain 168, Acta Crystallographica Section F-Structural Biology Communications, v. 67, n. Pt 5, p. 618-622, 2011. DOI: 10.1107/s1744309111010414

Sanfelici, L.; de Mattos, F.. Photon-beam stabilization systems for the MX2 beamline at LNLS, Nuclear Instruments & Methods in Physics Research Section A-Accelerators Spectrometers Detectors and Associated Equipment, v. 649, p.97-100, 2011. DOI: 10.1016/j.nima.2010.12.069

Guimarães, B. G.; Barbosa, R. L.; Soprano, A. S.; Campos, B. M.; de Souza, T. A.; Tonoli, C. C. C.; Paes Leme, A. F.; Murakami, M. T.; Benedetti, C. E.. Plant pathogenic bacteria utilize biofilm growth-associated repressor (BigR), a novel winged-helix redox switch, to control hydrogen sulfide detoxification under hypoxia, Journal of Biological Chemistry, v. 286, n. 29, p. 26148-26157, 2011. DOI: 10.1074/jbc.m111.234039

Silva, H. C.; Bari, A.F.; Pereira-Júnior, F. N.; Simões, R. C.; Barroso-Neto, I.L.; Pereira, M.G.; Nobre, C.B.; Nascimento, K. S.; Rocha, B. A. M.; Delatorre, P.; Nagano, C. S.; Assreuy, A. M. S.; Cavada, B. S.. Purification and partial characterization of a new pro-inflammatory lectin from Bauhinia bauhinioides Mart (Caesalpinoideae) seeds, Protein and Peptide Letters, v.18, n.4, p.396-402, 2011. DOI: 10.2174/092986611794653987

Textor, L. C.; Santos, Ja. C.; Cuadrado, N. H.; Roig, M. G.; Zhandan, G. G.; Shnyrov, V. L.; Polikarpov, I.. Purification, crystallization and preliminary crystallographic analysis of peroxidase from the palm tree Chamaerops excelsa, Acta Crystallographica Section F-Structural Biology Communications, v. 67, pt 12, p. 1641- 1644, 2011. DOI: 10.1107/s1744309111039030

Bezerra, E. H. S.; Rocha, B. A. M.; Nagano, C. S.; Bezerra, G. A.; Moura, T. R.; Bezerra, M. J. B.; Benevides, R. G.; Sampaio, A. H.; Assreuy, A. M. S.; Delatorre, P.; Cavada, B. S.. Structural analysis of ConBr reveals molecular correlation between the carbohydrate recognition domain and endothelial NO synthase activation, Biochemical and Biophysical Research Communications, v.408, n.4, p.566-570, 2011. DOI: 10.1016/j.bbrc.2011.04.061

Santos, J. I.; Cardoso, F. F.; Soares, A. M.; Dal Pai Silva, M; Gallacci, M.; Fontes, M. R. M.. Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA(2) Inhibition, PloS One, v. 6, n. 12, p. e28521, 2011. DOI: 10.1371/journal.pone.0028521

Rocha, B. A. M.; Delatorre, P.; Oliveira, T. M.; Benevides, R. G.; Pires, A. F.; Sousa, A. A. S.; Souza, L. A. G.; Assreuy, A. M. S.; Debray, H.; de Azevedo Jr., W. F.; Sampaio, A. H.; Cavada, B. S.. Structural basis for both pro- and anti-inflammatory response induced by mannose-specific legume lectin from Cymbosema roseum, Biochimie, v. 93, n. 5, p. 806-816, 2011. DOI: 10.1016/j.biochi.2011.01.006

Santos, C. R.; Tonoli, C. C. C.; Trindade, D. M.; Betzel, C.; Takata, H.; Kuriki, T.; Kanai, T.; Imanaka, T.; Arni, R. K.; Murakami, M. T.. Structural basis for branching-enzyme activity of glycoside hydrolase family 57: structure and stability studies of a novel branching enzyme from the hyperthermophilic archaeon Thermococcus Kodakaraensis KOD1, Proteins-Structure Function and Bioinformatics, v.79, n.2, p.547-557, 2011. DOI: 10.1002/prot.22902

Takeda, A. A. S.; Barros, A.C.; Chang,C-W; Kobe, B.; Fontes, M. R. M.. Structural Basis of Importin-alpha-Mediated Nuclear Transport for Ku70 and Ku80, Journal of Molecular Biology, v.412, n.2, p.226-234, 2011. DOI: 10.1016/j.jmb.2011.07.038

dos Santos, J. I.; Cintra-Francischinelli, M.; Borges, R. J.; Fernandes, C. A. H.; Pizzo, P.; Cintra, A. C. O.; Braz, A. S. K.; Soares, A. M.; Fontes, M. R. M.. Structural, functional, and bioinformatics studies reveal a new snake venom homologue phospholipase A(2) class, Proteins-Structure Function and Bioinformatics, v. 79, n. 1, p. 61-78, 2011. DOI: 10.1002/prot.22858

Giuseppe, P. O.; Ullah, A.; Silva, D. T.; Gremski, L. H.; Wille, A. C. M.; Moreira, D. C.; Ribeiro, A. S.; Chaim, O. M.; Murakami, M. T.; Veiga, S. S.; Arni, R. K.. Structure of a novel class II phospholipase D: catalytic cleft is modified by a disulphide bridge, Biochemical and Biophysical Research Communications, v. 409, n.4, n. 622-627, 2011. DOI: 10.1016/j.bbrc.2011.05.053

Souza, T.A.C.B.; Santos, C. R.; Oldiges, D. P.; Ruller, R.; Prade, R.; Squina, F. M.; Murakami, M. T.. Structure of a novel thermostable GH51 alpha-L-arabinofuranosidase from Thermotoga petrophila RKU-1, Protein Science, v. 20, n. 9, p. 1632-1637, 2011. DOI: 10.1002/pro.693

Trivella, D. B. B.; Sairre, M. I.; Foguel, D.; Lima, L. M. T. R.; Polikarpov, I.. The binding of synthetic triiodo L-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition, Journal of Structural Biology, v. 173, n. 2, p. 323- 332, 2011. DOI: 10.1016/j.jsb.2010.10.003

Cabrera, R.; Baez, M.; Pereira, H. M.; Caniuguir, A.; Garratt, R. C.; Babul, J.. The crystal complex of phosphofructokinase-2 of Escherichia coli with fructose-6-phosphate. Kinetic and structural analysis of the allosteric ATP inhibition, Journal of Biological Chemistry, v. 286, n. 7, p. 5774-5783, 2011. DOI: 10.1074/jbc.M110.163162

2010

Pereira, H. M.; Rezende, M. M.; Castilho, M. S.; Oliva, G.; Garratt, R. C.. Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni, Acta Crystallographica Section D-Biological Crystallography, v. 66, pt. 1, p. 73-79, 2010. DOI: 10.1107/s0907444909045715

Franco, J. L.; Trevisan, R.; Posser, T.; Trivella, D. B. B.; Hoppe, R.; Rosa, J. M.; Dinslaken, D. F.; Decker, H.; Tasca, C. I.; Leal, R. B.; Marques, M. R.F.; Bainy, A. C. D.; Dafre, A. L.. Biochemical alterations in caged Nile tilapia Oreochromis niloticus, Ecotoxicology and Environmental Safety, v. 73, n. 5, p. 864-872, 2010. DOI: 10.1016/j.ecoenv.2010.03.002

Santos, C. R.; Squina, F. M.; Meza, A. N.; Ruller, R.; Prade, R. A.; Murakami, M. T.. Cloning, expression, purification, crystallization and preliminary X-ray diffraction studies of the catalytic domain of a hyperthermostable endo-1,4-ß- D -mannanase from Thermotoga petrophila RKU-1, Acta Crystallographica Section F-Structural Biology Communications, v. 66, n. 9, p. 1078-1081, 2010. DOI: 10.1107/s1744309110029131

Fernandes, C. A. H.; Marchi-Salvador, D. P.; Salvador, G. M.; Silva, M. C. O.; Costa, T. R.; Soares, A. M.; Fontes, M. R. de M.. Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca2+-binding loop region for the catalytically inactive Lys49-PLA(2)s, Journal of Structural Biology, v. 171, n. 1, p. 31-43, 2010. DOI: 10.1016/j.jsb.2010.03.019

Trivella, D. B. B.; Bleicher, L.; Palmieri, L. de C.; Wiggers, H. J.; Montanari, C. A.; Kelly, J. W.; Lima, L. M. T. R.; Foguel, D.; Polikarpov, I.. Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding, Journal of Structural Biology, v. 170, n. 3, p. 522-531, 2010. DOI: 10.1016/j.jsb.2010.03.002

Watanabe, L.; Moura, P. R. de; Bleicher, L.; Nascimento, A. S.; Zamorano, L. S.; Calvete, J. J.; Sanz, L.; Pérez, A.; Bursakov, S.; Roig, M. G.; Shnyrov, V. L.; Polikarpov, I.. Crystal structure and statistical coupling analysis of highly glycosylated peroxidase from royal palm tree (Roystonea regia), Journal of Structural Biology, v. 169, n. 2, p. 226-242 , 2010. DOI: 10.1016/j.jsb.2009.10.009

dos Santos, J. I.; Santos-Filho, N. A.; Soares, A. M.; Fontes, M. R. M.. Crystallization and preliminary X-ray crystallographic studies of a Lys49-phospholipase A(2) homologue from Bothrops pirajai venom complexed with rosmarinic acid, Acta Crystallographica Section F-Structural Biology Communications, v. 66, pt. 6, p. 699-701, 2010. DOI: 10.1107/s1744309110013709

Cheleski, J.; Wiggers, H. J.; Citadini, A. P.; Costa Filho, A. J.; Nonato, M. C.; Montanari, C. A.. Kinetic mechanism and catalysis of Trypanosoma cruzi dihydroorotate dehydrogenase enzyme evaluated by isothermal titration calorimetry, Analytical Biochemistry, v. 399, n. 1, p. 13-22, 2010. DOI: 10.1016/j.ab.2009.11.018

Palmieri, L. de C.; Lima, L. M. T. R.; Freire, J. B. B.; Bleicher, L.; Polikarpov, I.; Almeida, F. C. L.; Foguel, D.. Novel Zn2+-binding Sites in Human Transthyretin IMPLICATIONS FOR AMYLOIDOGENESIS AND RETINOL-BINDING PROTEIN RECOGNITION, Journal of Biological Chemistry, v. 285, n. 41, p. 31731- 31741, 2010. DOI: 10.1074/jbc.M110.157206

Martinez, L.; Souza, P. C. T.; Garcia, W.; Batista, F. A. H.; Portugal, R. V.; Nascimento, A. S.; Nakahira, M.; Lima, L. M. T. R.; Polikarpov, I.; Skaf, M. S.. On the denaturation mechanisms of the ligand binding domain of thyroid hormone receptors, Journal of Physical Chemistry B, v. 114 (3): p. 1529-1540 (2010). DOI: 10.1021/jp911554p

Yang, S. N. Y.; Takeda, A. A. S.; Fontes, M. R. M.; Harris, J. M.; Jans, D. A.; Kobe, B.. Probing the specificity of binding to the major nuclear localization sequence-binding site of importin-alpha using oriented peptide library screening, Journal of Biological Chemistry, v. 285, n. 26, p. 19935-19946, 2010. DOI: 10.1074/jbc.m109.079574

Colussi, F.; Textor, L. C.; Serpa, V. I.; Maeda, R. N.; Pereira Jr., N.; Polikarpov, I.. Purification, crystallization and preliminary crystallographic analysis of the catalytic domain of the extracellular cellulase CBHI from Trichoderma harzianum, Acta Crystallographica Section F-Structural Biology Communications, v.66, n. 9, p. 1041- 1044, 2010. DOI: 10.1107/s1744309110026886

Horta, B. B.; de Oliveira, M. A.; Discola, K. F.; Cussiol, J. R. R.; Soares Netto, L. E.. Structural and Biochemical Characterization of Peroxiredoxin Q beta from Xylella fastidiosa CATALYTIC MECHANISM AND HIGH REACTIVITY, Journal of Biological Chemistry, v. 285, n. 21, p.16051-16065, 2010. DOI: 10.1074/jbc.M109.094839

Trivella, D. B. B.; Ferreira Jr., J. R.; Dumoutier, L.; Renauld, J. C.; Polikarpov, I.. Structure and function of interleukin-22 and other members of the interleukin-10 family, Cellular and Molecular Life Sciences, v. 67, n.17, p. 2909-2935, 2010. DOI: 10.1007/s00018-010-0380-0

Santos, C. R.; Meza, A. N.; Hoffmam, Z. B.; Cota, J.; Alvarez, T.M.; Ruller, R.; Giesel, G. M.; Verli, H.; Squina, F. M.; Prade, R. A.; Murakami, M. T.. Thermal-induced conformational changes in the product release area drive the enzymatic activity of xylanases 10B: Crystal structure, conformational stability and functional characterization of the xylanase 10B from Thermotoga petrophila RKU-1, Biochemical and Biophysical Research Communications, v. 403, n. 2, p. 214-219, 2010. DOI: 10.1016/j.bbrc.2010.11.010

2009

Moura, P. R. de, Watanabe, L.; Bleicher, L.; Colau, D.; Dumoutier, L.; Lemaire, M. M.; Renauld, J. C.; Polikarpov, I.. Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22. FEBS Letters, 583: 1072-1077 (2009).

Hauk, P.; Guzzo, C. R.; Ho, P. L.; Farah, C. S.. Crystallization and preliminary X-ray analysis of LipL32 from Leptospira interrogans serovar copenhageni. Acta Crystallographica F, 65: 307-309 (2009).

Watanabe, L.; Moura, P. R. de, Nascimento, A. S.; Colau, D.; Dumoutier, L.; Renauld, J. C.; Polikarpov, I.. Crystallization and preliminary X-ray diffraction analysis of human IL-22 bound to its soluble decoy receptor IL-22BP. Acta Crystallographica F, 65: 102-104 (2009).

dos Santos, C. R.; Fessel, M. R.; Vieira, L. C.; Krieger, M. A.; Goldenberg, S.; Guimarães, B. G.; Zanchin, N. I. T.; Barbosa, J. A. R. G.. Crystallization and preliminary X-ray diffraction analysis of Q4DV70 from Trypanosoma cruzi, a hypothetical protein with a putative thioredoxin domain. Acta Crystallographica F, 65: 641-644 (2009).

Moura, T. R.; Bezerra, G. A.; Bezerra, M. J. B.; Bezerra, E. H. S.; Benevides, R. G.; Rocha, B. A. M.; Souza, L. A. G.; Delatorre, P.; Nagano, C. S.; Cavada, B. S.. Crystallization and preliminary X-ray diffraction analysis of the lectin from Canavalia boliviana Piper seeds. Acta Crystallographica F, 65, 213-215 (2009).

Guzzo, C. R.; Farah, C. S.. Expression, crystallization and preliminary crystallographic analysis of PilZxac1133 from Xanthomonas axonopodis pv. citri. Acta Crystallographica F, 65: 304-306 (2009).

Squina, F. M.; Prade, R. A.; Wang, H.; Murakami, M. T.. Expression, purification, crystallization and preliminary crystallographic analysis of an endo-1,5-alpha-L-arabinanase from hyperthermophilic Thermotoga petrophila. Acta Crystallographica F, v. 65, p, 902-905, 2009.

Martinez, L.; Nascimento, A. S.; Nunes, F. M.; Phillips, P. W.; Aparicio, R.; Dias, S. M. G.; Figueira. A. C. M.; Lin, J. H.; Nguyen, P.; Apriletti, J. W.; Neves, F. A. R.; Baxter, J. D.; Webb, P.; Skaf, M. S.; Polikarpov, I.. Gaining ligand selectivity in thyroid hormone receptors via entropy. Proceedings of the National Academy of Sciences USA, 106: 20717-20722 (2009).

Guzzo, C. R.; Salinas, R. K.; Andrade, M. O.; Farah, C. S.. PILZ protein structure and interactions with PILB and the FIMX EAL domain: implications for control of type IV pilus biogenesis. Journal of Molecular Biology, 393: 848-866 (2009).

Tonoli, C. C. C.; Vieira, P. S.; Ward, J.; Arni, R. K.; de Oliveira, A. H. C.; Murakami, M. T.. Production, purification, crystallization and preliminary X-ray diffraction studies of the nucleoside, diphosphate kinase b from Leishmania major. Acta Crystallographica F, 65: 1116-1119 (2009).

Hauk, P.; Guzzo, C. R.; Ramos, H. R.; Ho, P. L.; Farah, C. S.. Structure and calcium-binding activity of LipL32, the major surface antigen of pathogenic Leptospira sp.. Journal of Molecular Biology, 390: 722-736 (2009).

Guimarães, B. G.; Sanfelici, L.; Neuenschwander, R. T.; Rodrigues, Fl.; Grizolli, W. C.; Raulik, M. A.; Piton, J. R.; Meyer, B. C.; Nascimento, A. S.; Polikarpov, I.. The MX2 macromolecular crystallography beamline: a wiggler X-ray source at the LNLS. Journal of Synchrotron Radiation, 16: 69-75 (2009).

2008

da Silva, A. J.; Teles, R. C. L.; Esteves, G. F.; dos Santos, C. R.; Barbosa, J. A. R. G.; Freitas, S. M.. Purification, crystallization and preliminary crystallographic studies of SPCI-chymotrypsin complex at 2.8 angstrom resolution. Acta Crystallographica F, 64: 914-917 (2008).

Giuseppe, P. O.; Neves, F. O.; Nascimento, A. L. T. O.; Guimarães, B. G.. The leptospiral antigen Lp49 is a two-domain protein with putative protein binding function. Journal of Structural Biology, 163: 53-60 (2008).

Muniz, J. R. C.; Ambrosio, A. L. B.; Araujo, H. S. S.; Cominetti, M. R.; Silva, A. M. M.; Oliva, G.; Garratt, R. C.; Souza, D. H. F.. The tree-dimensional structure of bothropasin, the main hemorragic factor from Bothrops jararaca venom: Insights for a new classification of snake venom metalloprotease subgroups. Toxicon, 52: 807-816 (2008).

2007

Souza Jr.; F. G.; Soares, B. G.; Dahmouche, K.. Effect of preparation method on nanoscopic structure of conductive SBS/PANI blends: study using small-angle X-ray scattering. Journal of Polymer Science B, 45: 3069-3077 (2007).