Leader: Ana Carolina de Mattos Zeri
Number: +55 19 3518 2948
The MANACA Group is responsible by the project of the MANACA Beamline in the new synchrotron light source of the Brazilian Synchrotron Light Laboratory (LNLS), Sirius. This beamline will focus on Macromolecular Nano-Crystallography and Coherent Methods for Structural Biology.
The MANACA Group is also responsible for managing and operating the MX2 Beamline dedicated to X-ray Protein Crystallography in the current UVX synchrotron light source at LNLS. The team of researchers and technicians are responsible for assembling the instrumentation necessary for performing the experiments, and for advising users in the operation of the equipment, collection of data and processing of the data obtained in the MX2 beamline.
Manacá (MAcromolecular micro and NAnoCrystAllography ) will be the first macromolecular crystallography beamline of Sirius and will be optimized for micrometric and sub-micrometric focus. The project includes two experimental stations, also including beams with dimensions of 20×5, 10×5 and 5×5 micron, dedicated to the study of three-dimensional structures of macromolecules, particularly complex arrangements such as viruses, membrane proteins and protein complexes and ligands.
The MX2 beamline is an experimental station dedicated to Macromolecular Crystallography in the hard x-rays energy range (5 to 15 keV) with maximum flux at 8.5 keV. The station is available for conventional single wavelength data collection as well as for Single and Multiple-wavelength Anomalous Diffraction (SAD/MAD) experiments.